The largest domination of US currency ever printed was the $100,000 bill.  The bill featured 28th President of the United States, Woodrow Wilson.  The Bureau of Engraving and Printing only made these notes during a three-week stretch during December 1934 and January 1935.
Historical Facts

The largest domination of US currency ever printed was the $100,000 bill. The bill featured 28th President of the United States, Woodrow Wilson. The Bureau of Engraving and Printing only made these notes during a three-week stretch during December 1934 and January 1935.

There was also an assortment of other large denomination currencies printed in the late 1920's; a $500 bill featuring William McKinley, a $1,000 bill featuring Grover Cleveland, a $5,000 bill featu...

The largest domination of US currency ever printed was the $100,000 bill. The bill featured 28th President of the United States, Woodrow Wilson. The Bureau of Engraving and Printing only made these notes during a three-week stretch during December 1934 and January 1935.

There was also an assortment of other large denomination currencies printed in the late 1920's; a $500 bill featuring William McKinley, a $1,000 bill featuring Grover Cleveland, a $5,000 bill featuring James Madison, and a $10,000 bill featuring Salmon Chase.